All-purpose
healing gels familiar to fans of futuristic video games and movies
could be about to make the transition from sci-fi fantasy to real-world
medical tool thanks to a New York University student who has invented a
gel that can instantly halt bleeding in even the most serious of wounds.
Veti-Gel, the name chosen by NYU student Joe Landolina uses plant
polymers to rapidly solidify when applied to open wounds, and by a
bizarre coincidence was initially being developed under the name
Medi-Gel, the name of a fictional healing gel from the Mass Effect video
game series with almost identical properties.
Humans Invent spoke to Joe Landolina about the development of
Veti-Gel, and how in just a few years he went from high-school science
geek to possibly securing a deal with the US military.
Stops bleeding
“In all of our tests we found we were able to immediately stop
bleeding,” says Landolina. “Your skin has this thing called the
extracellular matrix,” he explains. “It’s kind of a mesh of molecules
and sugars and protein that holds your cells in place.”
Landolina synthesises his own extracellular matrix (ECM) using plant
polymers, which can form a liquid when broken up into pieces. He says,
“So it goes into the wound and the pieces of the synthetic ECM in the
gel will recognise the pieces of the real ECM in the wound and they’ll
link together. It will re-assemble into something that looks like, feels
like and acts like skin.”
In all of our tests we found we were able to immediately stop bleeding
If Veti-Gel works as well as Landolina claims, it would be of obvious
interest to the military, where a quick response to severe bleeding can
make the difference between life and death. Current blood-clotting
agents still require a medic to apply pressure, and take up to three
minutes to take effect.
“We haven’t entered formal talks, but I’ve been talking to a few
officials in the military who really like the product,” says Landolina.
“I’ve spoken to DARPA about it. We’re definitely looking at the military
as one of our main customers,” he adds.
Interestingly, Veti-Gel doesn’t just stop bleeding but seems to
initiate the healing process. “It works in three ways,” says Landolina.
“The first way is it works as a tissue adhesive,” he explains. “It
actually holds its own pressure onto the wound so you don’t have to do
it. Secondly, when it touches the blood, it does something called
activating Factor 12.”
This activates fibrin, which is the polymer you need to make a blood
clot, explains Landolina. “Finally, it activates platelet cells.” The
gel causes these to bind to the fibrin, causing a tight seal. Landolina
says the speed at which this process happens is what triggers the
healing process. “We don’t have all the testing to back it up yet – but
it should allow it to heal faster over time,” he says.
Tissue engineering
Landolina was interested in science from a young age, and having a
vineyard in the family gave him access to a lab when he was a child.
He says, “I was always very interested in the medical field since
before I was in high-school. My family had a winery in upstate New York,
so we had chemistry labs there and I used to be able to experiment
around. I learned the ropes very early, my grandfather taught me
everything – he was a wine maker and a chemist.”
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Landolina laid the foundations for his later work while still in high
school: “I did summer programs at Columbia University. While I was
there I learnt how to do tissue engineering, which really got me
interested in the bioengineering side of medicine.”
But it was after he graduated from high school that Landolina started
to attract attention with Veti-Gel. Back in 2011, he entered two
college competitions with his business partner Isaac Miller, and it was
their success in those competitions that led to the formation of their
company, Suneris, Inc.
Landolina says, “We ended up getting second place at the business
school which is where [Isaac Miller] was from and we took first place at
the engineering school which is where I was from. And with that we got
so much interest that we decided to keep going and turn it into a real
company.”
Platform technology
The past two years have seen Landolina and Miller develop their
company and their product, now working under the supervision of
cardiovascular surgeon Dr Herbert Dardik at Englewood Hospital in New
Jersey. Landolina is also currently studying for a bachelor’s degree in
biomolecular and chemical engineering and a masters in biomedical
engineering simultaneously. Needless to say, the future looks promising
for Joe Landolina and his miracle healing gel.
We’re definitely looking at the military as one of our main customers
He says, “The gel is what we call a platform technology, it’s very
biocompatible – your body recognises it, and you can mix just about
anything into it. We’re doing tests to see if we can actually make it
work for healing wounds that won’t heal by adding in therapeutics or
drugs; you can put antibiotics into it, you can put just about anything
you want into it.”
Landolina has begun the process of securing approval from the US Food
and Drug Administration. He says, “The gel, once it gets FDA approval,
has a huge amount of ramifications, not only having something that can
be available to every medic, so that you can immediately stop traumatic
bleeding, but also something surgeons use in the operating room, so that
if you have some bleeding that arises on the operating table you don’t
lose the patient.”
But Landolina also envisages more everyday uses for Veti-Gel: “Every
mother has something in their purse, just so that if their kid cuts
themself, you can slap it on, and it takes the place of a liquid
bandage. All the way to care of the elderly where you have bed sores,
you can put this on – hopefully it can work on healing the ulcers. We’re
just trying to work out where it fits into the grand scheme of things.”
Clinical trials will begin around the same time as Veti-Gel is
released for the military, Landolina says, which may take up to a year
and a half. But until then, you’ll just have to settle for a plaster and
a couple of paracetamol.
For more information go to
Suneris, Inc.